Transcriptome analysis of microglia in a mouse model of Rett syndrome: differential expression of genes associated with microglia/macrophage activation and cellular stress

BACKGROUND: Rett syndrome (RTT) is a severe, neurodevelopmental disorder primarily affecting girls, characterized by progressive loss of cognitive, social, and motor skills after a relatively brief period of typical development. It is usually due to de novo loss of function mutations in the X-linked...

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Detalles Bibliográficos
Autores principales: Zhao, Dejian, Mokhtari, Ryan, Pedrosa, Erika, Birnbaum, Rayna, Zheng, Deyou, Lachman, Herbert M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372344/
https://www.ncbi.nlm.nih.gov/pubmed/28367307
http://dx.doi.org/10.1186/s13229-017-0134-z

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