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Oridonin effectively reverses the drug resistance of cisplatin involving induction of cell apoptosis and inhibition of MMP expression in human acute myeloid leukemia cells

Cisplatin is the first generation platinum-based chemotherapy agent. However, the extensive application of cisplatin inevitably causes drug resistance, which is a major obstacle to cancer chemotherapy. Oridonin is a diterpenoid isolated from Rabdosia rubescens with potent anticancer activity. The ai...

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Detalles Bibliográficos
Autores principales:	Zhang, Yuan, Wang, Lihua, Zi, Youmei, Zhang, Lingxiu, Guo, Yan, Huang, Yan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372424/ https://www.ncbi.nlm.nih.gov/pubmed/28386196 http://dx.doi.org/10.1016/j.sjbs.2017.01.042

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