Permeation of Polymethoxyflavones into the Mouse Brain and Their Effect on MK-801-Induced Locomotive Hyperactivity

Accumulating data have indicated that citrus polymethoxyflavones (PMFs) have the ability to affect brain function. In the present study, we showed that 3,5,6,7,8,3′,4′-heptamethoxy- flavone (HMF) given intraperitoneally to mice was immediately detected in the brain and that the permeability of the b...

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Detalles Bibliográficos
Autores principales: Okuyama, Satoshi, Miyazaki, Kohei, Yamada, Rie, Amakura, Yoshiaki, Yoshimura, Morio, Sawamoto, Atsushi, Nakajima, Mitsunari, Furukawa, Yoshiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372505/
https://www.ncbi.nlm.nih.gov/pubmed/28245567
http://dx.doi.org/10.3390/ijms18030489

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372505/
https://www.ncbi.nlm.nih.gov/pubmed/28245567
http://dx.doi.org/10.3390/ijms18030489

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