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Establishment of HK-2 Cells as a Relevant Model to Study Tenofovir-Induced Cytotoxicity

Tenofovir (TFV) is an antiviral drug approved for treating Human Immunodeficiency Virus (HIV) and Hepatitis B. TFV is administered orally as the prodrug tenofovir disoproxil fumarate (TDF) which then is deesterified to the active drug TFV. TFV induces nephrotoxicity characterized by renal failure an...

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Detalles Bibliográficos
Autores principales:	Murphy, Rachel A., Stafford, Reagan M., Petrasovits, Brooke A., Boone, Megann A., Valentovic, Monica A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372547/ https://www.ncbi.nlm.nih.gov/pubmed/28257038 http://dx.doi.org/10.3390/ijms18030531

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