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A New Oleanolic Acid Derivative against CCl(4)-Induced Hepatic Fibrosis in Rats

A novel hepatoprotective oleanolic acid derivative, 3-oxours-oleana-9(11), 12-dien-28-oic acid (Oxy-Di-OA), has been reported. In previous studies, we found that Oxy-Di-OA presented the anti-HBV (Hepatitis B Virus) activity (IC(50) = 3.13 µg/mL). Remarkably, it is superior to lamivudine in the inhib...

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Detalles Bibliográficos
Autores principales:	Xiang, Hongjun, Han, Yaotian, Zhang, Yuzhong, Yan, Wenqiang, Xu, Bing, Chu, Fuhao, Xie, Tianxin, Jia, Menglu, Yan, Mengmeng, Zhao, Rui, Wang, Penglong, Lei, Haimin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372569/ https://www.ncbi.nlm.nih.gov/pubmed/28272302 http://dx.doi.org/10.3390/ijms18030553

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