Cargando…

Caloric Restriction Protects against Lactacystin-Induced Degeneration of Dopamine Neurons Independent of the Ghrelin Receptor

Parkinson’s disease (PD) is a neurodegenerative disorder, characterized by a loss of dopamine (DA) neurons in the substantia nigra pars compacta (SNc). Caloric restriction (CR) has been shown to exert ghrelin-dependent neuroprotective effects in the 1-methyl-4-phenyl-1,2,3,6-tetrathydropyridine (MPT...

Descripción completa

Detalles Bibliográficos
Autores principales:	Coppens, Jessica, Bentea, Eduard, Bayliss, Jacqueline A., Demuyser, Thomas, Walrave, Laura, Albertini, Giulia, Van Liefferinge, Joeri, Deneyer, Lauren, Aourz, Najat, Van Eeckhaut, Ann, Portelli, Jeanelle, Andrews, Zane B., Massie, Ann, De Bundel, Dimitri, Smolders, Ilse
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372574/ https://www.ncbi.nlm.nih.gov/pubmed/28273852 http://dx.doi.org/10.3390/ijms18030558

Ejemplares similares

Ketamine Does Not Exert Protective Properties on Dopaminergic Neurons in the Lactacystin Mouse Model of Parkinson’s Disease
por: Deneyer, Lauren, et al.
Publicado: (2018)

Aged xCT-Deficient Mice Are Less Susceptible for Lactacystin-, but Not 1-Methyl-4-Phenyl-1,2,3,6- Tetrahydropyridine-, Induced Degeneration of the Nigrostriatal Pathway
por: Bentea, Eduard, et al.
Publicado: (2021)

Are vesicular neurotransmitter transporters potential treatment targets for temporal lobe epilepsy?
por: Van Liefferinge, Joeri, et al.
Publicado: (2013)

Nigral proteasome inhibition in mice leads to motor and non-motor deficits and increased expression of Ser129 phosphorylated α-synuclein
por: Bentea, Eduard, et al.
Publicado: (2015)

Absence of system x(c)(−) on immune cells invading the central nervous system alleviates experimental autoimmune encephalitis
por: Merckx, Ellen, et al.
Publicado: (2017)

Inhibition of Connexin43 Hemichannels Impairs Spatial Short-Term Memory without Affecting Spatial Working Memory
por: Walrave, Laura, et al.
Publicado: (2016)

Targeting the Ghrelin Receptor as a Novel Therapeutic Option for Epilepsy
por: Buckinx, An, et al.
Publicado: (2021)

Higher susceptibility to 6 Hz corneal kindling and lower responsiveness to antiseizure drugs in mouse models of Alzheimer's disease
por: Vande Vyver, Maxime, et al.
Publicado: (2022)

Critical Evaluation of Acetylcholine Determination in Rat Brain Microdialysates using Ion-Pair Liquid Chromatography with Amperometric Detection
por: De Bundel, Dimitri, et al.
Publicado: (2008)

Current Approaches to Monitor Macromolecules Directly from the Cerebral Interstitial Fluid
por: Custers, Marie-Laure, et al.
Publicado: (2022)

The intracerebral injection of Aβ(1-42) oligomers does not invariably alter seizure susceptibility in mice
por: Vande Vyver, Maxime, et al.
Publicado: (2023)

12.3 SYSTEM XC- AS A NOVEL MODULATOR OF CORTICOSTRIATAL NEUROTRANSMISSION
por: Bentea, Eduard, et al.
Publicado: (2018)

Formal synthesis of (+)-lactacystin from l-serine
por: Bulman Page, Philip C., et al.
Publicado: (2019)

Ghrelin is the metabolic link connecting calorie restriction to neuroprotection
por: Bayliss, Jacqueline A., et al.
Publicado: (2016)

Lactacystin-induced kidney fibrosis: Protection by melatonin and captopril
por: Repova, Kristina, et al.
Publicado: (2022)

The Proteasome Inhibition Model of Parkinson’s Disease
por: Bentea, Eduard, et al.
Publicado: (2017)

Chronic Sulfasalazine Treatment in Mice Induces System x(c) (−) - Independent Adverse Effects
por: Verbruggen, Lise, et al.
Publicado: (2021)

Lactacystin-Induced Model of Hypertension in Rats: Effects of Melatonin and Captopril
por: Simko, Fedor, et al.
Publicado: (2017)

Anchanling reduces pathology in a lactacystin- induced Parkinson's disease model☆
por: Li, Yinghong, et al.
Publicado: (2012)

Differential Effects of a Full and Biased Ghrelin Receptor Agonist in a Mouse Kindling Model
por: Buckinx, An, et al.
Publicado: (2019)

Repetitive transcranial magnetic stimulation for treatment of lactacystin-induced Parkinsonian rat model
por: Ba, Maowen, et al.
Publicado: (2017)

The histone deacetylase inhibitor nicotinamide exacerbates neurodegeneration in the lactacystin rat model of Parkinson's disease
por: Harrison, Ian F., et al.
Publicado: (2018)

Lactacystin: first-in-class proteasome inhibitor still excelling and an exemplar for future antibiotic research
por: Ōmura, Satoshi, et al.
Publicado: (2019)

The Good, the Bad and the Unknown Aspects of Ghrelin in Stress Coping and Stress-Related Psychiatric Disorders
por: Fritz, Eva Maria, et al.
Publicado: (2020)

Acylated but not des‐acyl ghrelin is neuroprotective in an MPTP mouse model of Parkinson's disease
por: Bayliss, Jacqueline A., et al.
Publicado: (2016)

Neuroanatomical characterization of the Nmu-Cre knock-in mice reveals an interconnected network of unique neuropeptidergic cells
por: Medrano, Mireia, et al.
Publicado: (2023)

Astrocytic Connexin43 Channels as Candidate Targets in Epilepsy Treatment
por: Walrave, Laura, et al.
Publicado: (2020)

Associated degeneration of ventral tegmental area dopaminergic neurons in the rat nigrostriatal lactacystin model of parkinsonism and their neuroprotection by valproate
por: Harrison, Ian F., et al.
Publicado: (2016)

Caloric restriction stimulates autophagy in rat cortical neurons through neuropeptide Y and ghrelin receptors activation
por: Ferreira-Marques, Marisa, et al.
Publicado: (2016)

Lack of Neuroprotective Effect of Celastrol Under Conditions of Proteasome Inhibition by Lactacystin in In Vitro and In Vivo Studies: Implications for Parkinson’s Disease
por: Konieczny, Jolanta, et al.
Publicado: (2014)

Proteasome inhibitor lactacystin enhances cisplatin cytotoxicity by increasing endoplasmic reticulum stress-associated apoptosis in HeLa cells
por: XU, YE, et al.
Publicado: (2015)

Ghrelin receptor agonist MK0677 and overnight fasting do not rescue deficient fear extinction in 129S1/SvImJ mice
por: Fritz, Eva Maria, et al.
Publicado: (2023)

Accelerated high frequency rTMS induces time-dependent dopaminergic alterations: a DaTSCAN brain imaging study in healthy beagle dogs
por: Xu, Yangfeng, et al.
Publicado: (2023)

The Role of Ghrelin in Neuroprotection after Ischemic Brain Injury
por: Spencer, Sarah J., et al.
Publicado: (2013)

Lifespan extension with preservation of hippocampal function in aged system x(c)(−)-deficient male mice
por: Verbruggen, Lise, et al.
Publicado: (2022)

The proteasome inhibitor lactacystin induces apoptosis and sensitizes chemo- and radioresistant human chronic lymphocytic leukaemia lymphocytes to TNF-alpha-initiated apoptosis.
por: Delic, J., et al.
Publicado: (1998)

Presence of proNGF-Sortilin Signaling Complex in Nigral Dopamine Neurons and Its Variation in Relation to Aging, Lactacystin and 6-OHDA Insults
por: Xia, Yi, et al.
Publicado: (2013)

The Protective Effect of Repeated 1MeTIQ Administration on the Lactacystin-Induced Impairment of Dopamine Release and Decline in TH Level in the Rat Brain
por: Wąsik, Agnieszka, et al.
Publicado: (2018)

Psychedelic-Induced Serotonin 2A Receptor Downregulation Does Not Predict Swim Stress Coping in Mice
por: Pędzich, Błażej D., et al.
Publicado: (2022)

Running Opposes the Effects of Social Isolation on Synaptic Plasticity and Transmission in a Rat Model of Depression
por: Gómez-Galán, Marta, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_i5prgoe4jukv9lbrgqiv38vilm