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AKT2 Blocks Nucleus Translocation of Apoptosis-Inducing Factor (AIF) and Endonuclease G (EndoG) While Promoting Caspase Activation during Cardiac Ischemia

The AKT (protein kinase B, PKB) family has been shown to participate in diverse cellular processes, including apoptosis. Previous studies demonstrated that protein kinase B2 (AKT2(−/−)) mice heart was sensitized to apoptosis in response to ischemic injury. However, little is known about the mechanis...

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Detalles Bibliográficos
Autores principales:	Yang, Shuai, Zhao, Xinmei, Xu, Hui, Chen, Fan, Xu, Yitao, Li, Zhe, Sanchis, Daniel, Jin, Liang, Zhang, Yubin, Ye, Junmei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372581/ https://www.ncbi.nlm.nih.gov/pubmed/28272306 http://dx.doi.org/10.3390/ijms18030565

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