PAMAM Dendrimers Cross the Blood–Brain Barrier When Administered through the Carotid Artery in C57BL/6J Mice

Drug delivery into the central nervous system (CNS) is challenging due to the blood–brain barrier (BBB) and drug delivery into the brain overcoming the BBB can be achieved using nanoparticles such as dendrimers. The conventional cationic dendrimers used are highly toxic. Therefore, the present study...

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Detalles Bibliográficos
Autores principales: Srinageshwar, Bhairavi, Peruzzaro, Sarah, Andrews, Melissa, Johnson, Kayla, Hietpas, Allison, Clark, Brittany, McGuire, Crystal, Petersen, Eric, Kippe, Jordyn, Stewart, Andrew, Lossia, Olivia, Al-Gharaibeh, Abeer, Antcliff, Aaron, Culver, Rebecca, Swanson, Douglas, Dunbar, Gary, Sharma, Ajit, Rossignol, Julien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372641/
https://www.ncbi.nlm.nih.gov/pubmed/28335421
http://dx.doi.org/10.3390/ijms18030628

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