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Nrf2 Regulates the Risk of a Diesel Exhaust Inhalation-Induced Immune Response during Bleomycin Lung Injury and Fibrosis in Mice

The present study investigated the effects of diesel exhaust (DE) on an experimental model of bleomycin (BLM)-induced lung injury and fibrosis in mice. BLM was intravenously administered to both Nrf2(+/+) and Nrf2(−/−) C57BL/6J mice on day 0. The mice were exposed to DE for 56 days from 28 days befo...

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Detalles Bibliográficos
Autores principales:	Li, Ying-Ji, Shimizu, Takako, Shinkai, Yusuke, Hirata, Yukiyo, Inagaki, Hirofumi, Takeda, Ken, Azuma, Arata, Yamamoto, Masayuki, Kawada, Tomoyuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372661/ https://www.ncbi.nlm.nih.gov/pubmed/28304344 http://dx.doi.org/10.3390/ijms18030649

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