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The Glyoxalase System and Methylglyoxal-Derived Carbonyl Stress in Sepsis: Glycotoxic Aspects of Sepsis Pathophysiology
Sepsis remains one of the leading causes of death in intensive care units. Although sepsis is caused by a viral, fungal or bacterial infection, it is the dysregulated generalized host response that ultimately leads to severe dysfunction of multiple organs and death. The concomitant profound metaboli...
Autores principales: | Schmoch, Thomas, Uhle, Florian, Siegler, Benedikt H., Fleming, Thomas, Morgenstern, Jakob, Nawroth, Peter P., Weigand, Markus A., Brenner, Thorsten |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372669/ https://www.ncbi.nlm.nih.gov/pubmed/28304355 http://dx.doi.org/10.3390/ijms18030657 |
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