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Effect of the ortho-hydroxy group of salicylaldehyde in the A(3) coupling reaction: A metal-catalyst-free synthesis of propargylamine
The synthesis of propargylamines via A(3) coupling mostly under metal-catalyzed procedures is well known. This work invented an unprecedented effect of salicylaldehyde, one of the A(3) coupling partners, which could lead to the formation of propargylamine, an important pharmaceutical building block,...
Autores principales: | Ghosh, Sujit, Biswas, Kinkar, Bhattacharya, Suchandra, Ghosh, Pranab, Basu, Basudeb |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Beilstein-Institut
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372705/ https://www.ncbi.nlm.nih.gov/pubmed/28405234 http://dx.doi.org/10.3762/bjoc.13.53 |
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