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Role of Pseudouridine Formation by Deg1 for Functionality of Two Glutamine Isoacceptor tRNAs
Loss of Deg1/Pus3 and concomitant elimination of pseudouridine in tRNA at positions 38 and 39 (ψ38/39) was shown to specifically impair the function of tRNA(Gln)(UUG) under conditions of temperature-induced down-regulation of wobble uridine thiolation in budding yeast and is linked to intellectual d...
Autores principales: | Klassen, Roland, Schaffrath, Raffael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372720/ https://www.ncbi.nlm.nih.gov/pubmed/28134782 http://dx.doi.org/10.3390/biom7010008 |
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