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Modulation of the Proteostasis Machinery to Overcome Stress Caused by Diminished Levels of t(6)A-Modified tRNAs in Drosophila
Transfer RNAs (tRNAs) harbor a subset of post-transcriptional modifications required for structural stability or decoding function. N(6)-threonylcarbamoyladenosine (t(6)A) is a universally conserved modification found at position 37 in tRNA that pair A-starting codons (ANN) and is required for prope...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372737/ https://www.ncbi.nlm.nih.gov/pubmed/28272317 http://dx.doi.org/10.3390/biom7010025 |