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Trm5 and TrmD: Two Enzymes from Distinct Origins Catalyze the Identical tRNA Modification, m(1)G37

The N(1)-atom of guanosine at position 37 in transfer RNA (tRNA) is methylated by tRNA methyltransferase 5 (Trm5) in eukaryotes and archaea, and by tRNA methyltransferase D (TrmD) in bacteria. The resultant modified nucleotide m(1)G37 positively regulates the aminoacylation of the tRNA, and simultan...

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Detalles Bibliográficos
Autores principales:	Goto-Ito, Sakurako, Ito, Takuhiro, Yokoyama, Shigeyuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372744/ https://www.ncbi.nlm.nih.gov/pubmed/28335556 http://dx.doi.org/10.3390/biom7010032

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