Cargando…

Hif-1α Overexpression Improves Transplanted Bone Mesenchymal Stem Cells Survival in Rat MCAO Stroke Model

Bone mesenchymal stem cells (BMSCs) death after transplantation is a serious obstacle impacting on the outcome of cell therapy for cerebral infarction. This study was aimed to investigate whether modification of BMSCs with hypoxia-inducible factor 1α (Hif-1α) could enhance the survival of the implan...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lv, Bingke, Li, Feng, Han, Jianbang, Fang, Jie, Xu, Limin, Sun, Chengmei, Hua, Tian, Zhang, Zhongfei, Feng, Zhiming, Jiang, Xiaodan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372780/ https://www.ncbi.nlm.nih.gov/pubmed/28424584 http://dx.doi.org/10.3389/fnmol.2017.00080

Ejemplares similares

Activated Microglia Induce Bone Marrow Mesenchymal Stem Cells to Produce Glial Cell-Derived Neurotrophic Factor and Protect Neurons Against Oxygen-Glucose Deprivation Injury
por: Lv, Bingke, et al.
Publicado: (2016)

Human umbilical cord mesenchymal stem cell-derived exosomal miR-146a-5p reduces microglial-mediated neuroinflammation via suppression of the IRAK1/TRAF6 signaling pathway after ischemic stroke
por: Zhang, Zhongfei, et al.
Publicado: (2021)

Mesenchymal stem cells inhibit lipopolysaccharide-induced inflammatory responses of BV2 microglial cells through TSG-6
por: Liu, Yi, et al.
Publicado: (2014)

Mesenchymal stem cell aggregation mediated by integrin α4/VCAM-1 after intrathecal transplantation in MCAO rats
por: Ran, Ye, et al.
Publicado: (2022)

Tracking Transplanted Bone Marrow Stem Cells and Their Effects in the Rat MCAO Stroke Model
por: Goldmacher, Gregory V., et al.
Publicado: (2013)

HIF-1α Overexpression Induces Angiogenesis in Mesenchymal Stem Cells
por: Razban, Vahid, et al.
Publicado: (2012)

Network Pharmacology Experiments Show That Emodin Can Exert a Protective Effect on MCAO Rats by Regulating Hif-1α/VEGF-A Signaling
por: Lv, Baojiang, et al.
Publicado: (2022)

Editorial: Neuroinflammation and neuroimmune response in experimental MCAO and ischemic stroke
por: Zhao, Yingzhe, et al.
Publicado: (2023)

HIF-1α attenuates neuronal apoptosis by upregulating EPO expression following cerebral ischemia-reperfusion injury in a rat MCAO model
por: Li, Jun, et al.
Publicado: (2020)

A study of optimal concentration range and time window of sevoflurane preconditioning for brain protection in MCAO rats
por: Deng, Ying, et al.
Publicado: (2020)

Mesenchymal stem cells protect against TBI-induced pyroptosis in vivo and in vitro through TSG-6
por: Feng, Zhiming, et al.
Publicado: (2022)

Spatiotemporal Protein Atlas of Cell Death-Related Molecules in the Rat MCAO Stroke Model
por: Yoon, Jeong Seon, et al.
Publicado: (2018)

Sun and survival with Hif1α
por: Tuma, Rabiya S.
Publicado: (2005)

Overexpression of carbonic anhydrase and HIF-1α in Wilms tumours
por: Dungwa, Josiah V, et al.
Publicado: (2011)

Bone Marrow Mesenchymal Stem Cells Overexpressing HIF-1α Prevented the Progression of Glucocorticoid-Induced Avascular Osteonecrosis of Femoral Heads in Mice
por: Zhang, Xin-Xin, et al.
Publicado: (2022)

HIF-1α is Overexpressed in Odontogenic Keratocyst Suggesting Activation of HIF-1α and NOTCH1 Signaling Pathways
por: Miranda da Costa, Natacha Malu, et al.
Publicado: (2019)

Adoptive transfer of immune subsets prior to MCAO does not exacerbate stroke outcome in splenectomized mice
por: Wang, Jianming, et al.
Publicado: (2015)

Optimizing intra-arterial hypothermia scheme for acute ischemic stroke in an MCAO/R rat model
por: Zeng, Yuqi, et al.
Publicado: (2023)

HIF-1α overexpression in mesenchymal stem cell-derived exosomes mediates cardioprotection in myocardial infarction by enhanced angiogenesis
por: Sun, Jiacheng, et al.
Publicado: (2020)

Overexpressed HIF-2α in Endothelial Cells Promotes Vascularization and Improves Random Pattern Skin Flap Survival
por: Morimoto, Atsushi, et al.
Publicado: (2014)

Knockdown of NRSF Alleviates Ischemic Brain Injury and Microvasculature Defects in Diabetic MCAO Mice
por: He, Cheng-Feng, et al.
Publicado: (2022)

Integrated analysis of the proteome and transcriptome in a MCAO mouse model revealed the molecular landscape during stroke progression
por: Li, Litao, et al.
Publicado: (2020)

The GHB analogue HOCPCA improves deficits in cognition and sensorimotor function after MCAO via CaMKIIα
por: Griem-Krey, Nane, et al.
Publicado: (2023)

HIF1α overexpression enhances diabetic wound closure in high glucose and low oxygen conditions by promoting adipose-derived stem cell paracrine function and survival
por: Xu, Jin, et al.
Publicado: (2020)

Integration of CNS survival and differentiation by HIF2α
por: Ko, C-Y, et al.
Publicado: (2011)

Allogeneic Mesenchymal Stromal Cells Overexpressing Mutant Human Hypoxia‐Inducible Factor 1‐α (HIF1‐α) in an Ovine Model of Acute Myocardial Infarction
por: Hnatiuk, Anna P., et al.
Publicado: (2016)

Intravenous Transplantation of Mesenchymal Stem Cells Reduces the Number of Infiltrated Ly6C(+) Cells but Enhances the Proportions Positive for BDNF, TNF-1α, and IL-1β in the Infarct Cortices of dMCAO Rats
por: Guan, Yunqian, et al.
Publicado: (2018)

The Impact of Ischemic Stroke on Gray and White Matter Injury Correlated With Motor and Cognitive Impairments in Permanent MCAO Rats: A Multimodal MRI-Based Study
por: Yang, Le, et al.
Publicado: (2022)

HIF1 and ID1 Interplay Confers Adaptive Survival to HIF1α-Inhibition
por: Geng, Hao, et al.
Publicado: (2021)

Histopathological Investigation of Different MCAO Modalities and Impact of Autologous Bone Marrow Mononuclear Cell Administration in an Ovine Stroke Model
por: Boltze, Johannes, et al.
Publicado: (2011)

PEGylated Erythropoietin Protects against Brain Injury in the MCAO-Induced Stroke Model by Blocking NF-κB Activation
por: Im, Jun Hyung, et al.
Publicado: (2020)

UPLC-Q-TOF/MS-Based Serum Metabolomics Reveals the Anti-Ischemic Stroke Mechanism of Nuciferine in MCAO Rats
por: Wu, Lanlan, et al.
Publicado: (2020)

Deep Sequencing of the Rat MCAO Cortexes Reveals Crucial circRNAs Involved in Early Stroke Events and Their Regulatory Networks
por: Wang, Chengtan, et al.
Publicado: (2021)

Cerebroprotective effects of Moringa oleifera derivatives extracts against MCAO ischemic stroke: A systematic review and meta-analysis
por: Cuschieri, Andea, et al.
Publicado: (2023)

The role of HIF-1α-VEGF pathway in bronchiolitis obliterans after lung transplantation
por: Xu, Haichao, et al.
Publicado: (2019)

Neuroprotective Effects of an Edible Pigment Brilliant Blue FCF against Behavioral Abnormity in MCAO Rats
por: Le, Jingyang, et al.
Publicado: (2022)

The effects of HIF-1α overexpression on renal injury, immune disorders and mitochondrial apoptotic pathways in renal ischemia/reperfusion rats
por: Li, Xiaoli, et al.
Publicado: (2020)

Comparison of MSC-Neurogenin1 administration modality in MCAO rat model
por: Shin, Dong Hoon, et al.
Publicado: (2016)

Coexisting flavonoids and administration route effect on pharmacokinetics of Puerarin in MCAO rats
por: Li, Pengyue, et al.
Publicado: (2020)

Bone Marrow-Derived Mesenchymal Stem Cells Maintain the Resting Phenotype of Microglia and Inhibit Microglial Activation
por: Yan, Ke, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_09ndhrvh7upp2geen94md1e06d