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Efr3a Insufficiency Attenuates the Degeneration of Spiral Ganglion Neurons after Hair Cell Loss

Sensorineural hearing loss (SNHL) is caused by an irreversible impairment of cochlear hair cells and subsequent progressive degeneration of spiral ganglion neurons (SGNs). Eighty-five requiring 3 (Efr3) is a plasma membrane protein conserved from yeast to human, and knockout of Efr3a was reported to...

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Detalles Bibliográficos
Autores principales: Hu, Haixia, Ye, Bin, Zhang, Le, Wang, Quan, Liu, Zhiwei, Ji, Suying, Liu, Qiuju, Lv, Jingrong, Ma, Yan, Xu, Ying, Wu, Hao, Huang, Fude, Xiang, Mingliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372784/
https://www.ncbi.nlm.nih.gov/pubmed/28424585
http://dx.doi.org/10.3389/fnmol.2017.00086