Overexpression of Human SOD1 Leads to Discrete Defects in the Cerebellar Architecture in the Mouse

The human superoxide dismutase 1 (SOD1) gene is responsible for neutralizing supercharged oxygen radicals within the cell. Mutation in SOD1 gene causes amyotrophic lateral sclerosis (ALS). Recent studies have shown involvement of the cerebellum in ALS, although the cerebellar contribution in SOD1 tr...

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Detalles Bibliográficos
Autores principales: Afshar, Pegah, Ashtari, Niloufar, Jiao, Xiaodan, Rahimi-Balaei, Maryam, Zhang, Xiaosha, Yaganeh, Behzad, Del Bigio, Marc R., Kong, Jiming, Marzban, Hassan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372795/
https://www.ncbi.nlm.nih.gov/pubmed/28424594
http://dx.doi.org/10.3389/fnana.2017.00022

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