Cargando…
Thioridazine: A Non-Antibiotic Drug Highly Effective, in Combination with First Line Anti-Tuberculosis Drugs, against Any Form of Antibiotic Resistance of Mycobacterium tuberculosis Due to Its Multi-Mechanisms of Action
This review presents the evidence that supports the use of thioridazine (TZ) for the therapy of a pulmonary tuberculosis infection regardless of its antibiotic resistance status. The evidence consists of in vitro and ex vivo assays that demonstrate the activity of TZ against all encountered Mycobact...
Autores principales: | Amaral, Leonard, Viveiros, Miguel |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372983/ https://www.ncbi.nlm.nih.gov/pubmed/28098814 http://dx.doi.org/10.3390/antibiotics6010003 |
Ejemplares similares
-
Anti-staphylococcal activity and mode of action of thioridazine photoproducts
por: Tozar, Tatiana, et al.
Publicado: (2020) -
Tools to develop antibiotic combinations that target drug tolerance in Mycobacterium tuberculosis
por: Greenstein, Talia, et al.
Publicado: (2023) -
The evolution of antibiotic resistance is associated with collateral drug phenotypes in Mycobacterium tuberculosis
por: Waller, Natalie J. E., et al.
Publicado: (2023) -
Developing Synergistic Drug Combinations To Restore Antibiotic Sensitivity in Drug-Resistant Mycobacterium tuberculosis
por: Omollo, Charles, et al.
Publicado: (2021) -
Bioenergetic Inhibitors: Antibiotic Efficacy and Mechanisms of Action in Mycobacterium tuberculosis
por: Hasenoehrl, Erik J., et al.
Publicado: (2021)