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Serum retinol-binding protein-induced endothelial inflammation is mediated through the activation of toll-like receptor 4

PURPOSE: Elevation of serum retinol-binding protein 4 (RBP4) induces inflammation in primary human retinal microvascular endothelial cells (HRECs) via a retinol-independent mechanism; thus, it may play a causative role in the development and progression of vascular lesions in diabetic retinopathy (D...

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Detalles Bibliográficos
Autores principales: Du, Mei, Martin, Ashley, Hays, Franklin, Johnson, Jennifer, Farjo, Rafal A., Farjo, Krysten M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2017
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5373036/
https://www.ncbi.nlm.nih.gov/pubmed/28400700