Cargando…
Studying human immunodeficiencies in humans: advances in fundamental concepts and therapeutic interventions
Immunodeficiencies reveal the crucial role of the immune system in defending the body against microbial pathogens. Given advances in genomics and other technologies, this is currently best studied in humans who have inherited monogenic diseases. Such investigations have provided insights into how ge...
| Autor principal: | |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
F1000Research
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5373415/ https://www.ncbi.nlm.nih.gov/pubmed/28408979 http://dx.doi.org/10.12688/f1000research.10594.1 |
| _version_ | 1782518771656687616 |
|---|---|
| author | Su, Helen |
| author_facet | Su, Helen |
| author_sort | Su, Helen |
| collection | PubMed |
| description | Immunodeficiencies reveal the crucial role of the immune system in defending the body against microbial pathogens. Given advances in genomics and other technologies, this is currently best studied in humans who have inherited monogenic diseases. Such investigations have provided insights into how gene products normally function in the natural environment and have opened the door to new, exciting treatments for these diseases. |
| format | Online Article Text |
| id | pubmed-5373415 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2017 |
| publisher | F1000Research |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-53734152017-04-12 Studying human immunodeficiencies in humans: advances in fundamental concepts and therapeutic interventions Su, Helen F1000Res Review Immunodeficiencies reveal the crucial role of the immune system in defending the body against microbial pathogens. Given advances in genomics and other technologies, this is currently best studied in humans who have inherited monogenic diseases. Such investigations have provided insights into how gene products normally function in the natural environment and have opened the door to new, exciting treatments for these diseases. F1000Research 2017-03-24 /pmc/articles/PMC5373415/ /pubmed/28408979 http://dx.doi.org/10.12688/f1000research.10594.1 Text en Copyright: © 2017 Su H http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The author(s) is/are employees of the US Government and therefore domestic copyright protection in USA does not apply to this work. The work may be protected under the copyright laws of other jurisdictions when used in those jurisdictions. |
| spellingShingle | Review Su, Helen Studying human immunodeficiencies in humans: advances in fundamental concepts and therapeutic interventions |
| title | Studying human immunodeficiencies in humans: advances in fundamental concepts and therapeutic interventions |
| title_full | Studying human immunodeficiencies in humans: advances in fundamental concepts and therapeutic interventions |
| title_fullStr | Studying human immunodeficiencies in humans: advances in fundamental concepts and therapeutic interventions |
| title_full_unstemmed | Studying human immunodeficiencies in humans: advances in fundamental concepts and therapeutic interventions |
| title_short | Studying human immunodeficiencies in humans: advances in fundamental concepts and therapeutic interventions |
| title_sort | studying human immunodeficiencies in humans: advances in fundamental concepts and therapeutic interventions |
| topic | Review |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5373415/ https://www.ncbi.nlm.nih.gov/pubmed/28408979 http://dx.doi.org/10.12688/f1000research.10594.1 |
| work_keys_str_mv | AT suhelen studyinghumanimmunodeficienciesinhumansadvancesinfundamentalconceptsandtherapeuticinterventions |