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Acute lymphoblastic leukaemia cells produce large extracellular vesicles containing organelles and an active cytoskeleton

Extracellular vesicles have been described in non-paracrine cellular interactions in cancer. We report a similar phenomenon in B-cell precursor (BCP) acute lymphoblastic leukaemia (ALL). Using advanced microscopy and high throughput screening, we further characterise a subset of large vesicles (LEVs...

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Detalles Bibliográficos
Autores principales: Johnson, Suzanne M., Dempsey, Clare, Parker, Catriona, Mironov, Aleksandr, Bradley, Helen, Saha, Vaskar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5373679/
https://www.ncbi.nlm.nih.gov/pubmed/28386390
http://dx.doi.org/10.1080/20013078.2017.1294339