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Acute lymphoblastic leukaemia cells produce large extracellular vesicles containing organelles and an active cytoskeleton
Extracellular vesicles have been described in non-paracrine cellular interactions in cancer. We report a similar phenomenon in B-cell precursor (BCP) acute lymphoblastic leukaemia (ALL). Using advanced microscopy and high throughput screening, we further characterise a subset of large vesicles (LEVs...
Autores principales: | Johnson, Suzanne M., Dempsey, Clare, Parker, Catriona, Mironov, Aleksandr, Bradley, Helen, Saha, Vaskar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5373679/ https://www.ncbi.nlm.nih.gov/pubmed/28386390 http://dx.doi.org/10.1080/20013078.2017.1294339 |
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