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Cadherins mediate cocaine-induced synaptic plasticity and behavioral conditioning
Drugs of abuse alter synaptic connections in the ‘reward circuit’ of the brain, which leads to long-lasting behavioral changes that underlie addiction. Here we show that cadherin adhesion molecules play a critical role in mediating synaptic plasticity and behavioral changes driven by cocaine. We dem...
Autores principales: | Mills, Fergil, Globa, Andrea K., Liu, Shuai, Cowan, Catherine M., Mobasser, Mahsan, Phillips, Anthony G., Borgland, Stephanie L., Bamji, Shernaz X. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5373847/ https://www.ncbi.nlm.nih.gov/pubmed/28192395 http://dx.doi.org/10.1038/nn.4503 |
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