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Evidence for the in vivo safety of insulated foamy viral vectors

Retroviral vector mediated stem cell gene therapy is a promising approach for the treatment of hematopoietic disorders. However, genotoxic side effects from integrated vector proviruses are a significant concern for the use of retroviral vectors in the clinic. Insulated foamy viral (FV) vectors are...

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Detalles Bibliográficos
Autores principales:	Browning, Diana L., Everson, Elizabeth M., Leap, David J., Hocum, Jonah D., Wang, Hao, Stamatoyannopoulos, George, Trobridge, Grant D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374020/ https://www.ncbi.nlm.nih.gov/pubmed/28024082 http://dx.doi.org/10.1038/gt.2016.88

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