Cargando…
Structure-Guided Identification of a Family of Dual Receptor-Binding PfEMP1 that Is Associated with Cerebral Malaria
Cerebral malaria is a deadly outcome of infection by Plasmodium falciparum, occurring when parasite-infected erythrocytes accumulate in the brain. These erythrocytes display parasite proteins of the PfEMP1 family that bind various endothelial receptors. Despite the importance of cerebral malaria, a...
Autores principales: | Lennartz, Frank, Adams, Yvonne, Bengtsson, Anja, Olsen, Rebecca W., Turner, Louise, Ndam, Nicaise T., Ecklu-Mensah, Gertrude, Moussiliou, Azizath, Ofori, Michael F., Gamain, Benoit, Lusingu, John P., Petersen, Jens E.V., Wang, Christian W., Nunes-Silva, Sofia, Jespersen, Jakob S., Lau, Clinton K.Y., Theander, Thor G., Lavstsen, Thomas, Hviid, Lars, Higgins, Matthew K., Jensen, Anja T.R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374107/ https://www.ncbi.nlm.nih.gov/pubmed/28279348 http://dx.doi.org/10.1016/j.chom.2017.02.009 |
Ejemplares similares
-
Plasmodium falciparum Expressing Domain Cassette 5 Type PfEMP1 (DC5-PfEMP1) Bind PECAM1
por: Berger, Sanne S., et al.
Publicado: (2013) -
Natural and Vaccine-Induced Acquisition of Cross-Reactive IgG-Inhibiting ICAM-1-Specific Binding of a Plasmodium falciparum PfEMP1 Subtype Associated Specifically with Cerebral Malaria
por: Olsen, Rebecca W., et al.
Publicado: (2018) -
Cerebral Plasmodium falciparum malaria: The role of PfEMP1 in its pathogenesis and immunity, and PfEMP1‐based vaccines to prevent it
por: Jensen, Anja Ramstedt, et al.
Publicado: (2019) -
Beninese children with cerebral malaria do not develop humoral immunity against the IT4-VAR19-DC8 PfEMP1 variant linked to EPCR and brain endothelial binding
por: Nunes-Silva, Sofia, et al.
Publicado: (2015) -
Erratum to: Beninese children with cerebral malaria do not develop humoral immunity against the IT4-VAR19-DC8 PfEMP1 variant linked to EPCR and brain endothelial binding
por: Nunes-Silva, Sofia, et al.
Publicado: (2016)