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Acanthopanax senticosus polysaccharides-induced intestinal tight junction injury alleviation via inhibition of NF-κB/MLCK pathway in a mouse endotoxemia model

AIM: To examine the effects of Acanthopanax senticosus polysaccharides (ASPS) on intestinal tight junction (TJ) disruption and nuclear factor-kappa B (NF-κB)/myosin light chain kinase (MLCK) activation in endotoxemia. METHODS: BALB/C mice (6-8-weeks-old) received continuous intragastric gavage of AS...

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Detalles Bibliográficos
Autores principales: Han, Jie, Li, Ji-Hong, Bai, Guang, Shen, Guo-Shun, Chen, Jing, Liu, Jia-Nan, Wang, Shuo, Liu, Xian-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374129/
https://www.ncbi.nlm.nih.gov/pubmed/28405145
http://dx.doi.org/10.3748/wjg.v23.i12.2175

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