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The Thrombopoietin Receptor: Structural Basis of Traffic and Activation by Ligand, Mutations, Agonists, and Mutated Calreticulin

A well-functioning hematopoietic system requires a certain robustness and flexibility to maintain appropriate quantities of functional mature blood cells, such as red blood cells and platelets. This review focuses on the cytokine receptor that plays a significant role in thrombopoiesis: the receptor...

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Detalles Bibliográficos
Autores principales: Varghese, Leila N., Defour, Jean-Philippe, Pecquet, Christian, Constantinescu, Stefan N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374145/
https://www.ncbi.nlm.nih.gov/pubmed/28408900
http://dx.doi.org/10.3389/fendo.2017.00059

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