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TET Methylcytosine Oxidases in T Cell and B Cell Development and Function

DNA methylation is established by DNA methyltransferases and is a key epigenetic mark. Ten-eleven translocation (TET) proteins are enzymes that oxidize 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC) and further oxidization products (oxi-mCs), which indirectly promote DNA demethylation. Her...

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Detalles Bibliográficos
Autores principales:	Tsagaratou, Ageliki, Lio, Chan-Wang J., Yue, Xiaojing, Rao, Anjana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374156/ https://www.ncbi.nlm.nih.gov/pubmed/28408905 http://dx.doi.org/10.3389/fimmu.2017.00220

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