Cargando…

Genetic determinants of serum vitamin B12 and their relation to body mass index

Lower serum vitamin B12 levels have been related to adverse metabolic health profiles, including adiposity. We used a Mendelian randomization design to test whether this relation might be causal. We included two Danish population-based studies (n(total) = 9311). Linear regression was used to test fo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Allin, Kristine H., Friedrich, Nele, Pietzner, Maik, Grarup, Niels, Thuesen, Betina H., Linneberg, Allan, Pisinger, Charlotta, Hansen, Torben, Pedersen, Oluf, Sandholt, Camilla H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Netherlands 2016
Materias:	Genetic Epidemiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374184/ https://www.ncbi.nlm.nih.gov/pubmed/27995393 http://dx.doi.org/10.1007/s10654-016-0215-x

Ejemplares similares

Urinary metabolomics reveals glycemic and coffee associated signatures of thyroid function in two population-based cohorts
por: Friedrich, Nele, et al.
Publicado: (2017)

Vitamin D Status and Cause-Specific Mortality: A General Population Study
por: Skaaby, Tea, et al.
Publicado: (2012)

Do Gene Variants Influencing Adult Adiposity Affect Birth Weight? A Population-Based Study of 24 Loci in 4,744 Danish Individuals
por: Andersson, Ehm A., et al.
Publicado: (2010)

Vitamin D Status and Chronic Obstructive Pulmonary Disease: A Prospective General Population Study
por: Skaaby, Tea, et al.
Publicado: (2014)

Genetic Correlation between Body Fat Percentage and Cardiorespiratory Fitness Suggests Common Genetic Etiology
por: Schnurr, Theresia M., et al.
Publicado: (2016)

The Association Between IGF-I and Insulin Resistance: A general population study in Danish adults
por: Friedrich, Nele, et al.
Publicado: (2012)

Variants Near MC4R Are Associated With Obesity and Influence Obesity-Related Quantitative Traits in a Population of Middle-Aged People: Studies of 14,940 Danes
por: Zobel, Dorit P., et al.
Publicado: (2009)

Association Testing of Novel Type 2 Diabetes Risk Alleles in the JAZF1, CDC123/CAMK1D, TSPAN8, THADA, ADAMTS9, and NOTCH2 Loci With Insulin Release, Insulin Sensitivity, and Obesity in a Population-Based Sample of 4,516 Glucose-Tolerant Middle-Aged Danes
por: Grarup, Niels, et al.
Publicado: (2008)

Cause-Specific Mortality According to Urine Albumin Creatinine Ratio in the General Population
por: Skaaby, Tea, et al.
Publicado: (2014)

Combined Analyses of 20 Common Obesity Susceptibility Variants
por: Sandholt, Camilla Helene, et al.
Publicado: (2010)

Genetic Architecture of Vitamin B(12) and Folate Levels Uncovered Applying Deeply Sequenced Large Datasets
por: Grarup, Niels, et al.
Publicado: (2013)

Correction: Genetic Variant SCL2A2 Is Associated with Risk of Cardiovascular Disease – Assessing the Individual and Cumulative Effect of 46 Type 2 Diabetes Related Genetic Variants
por: Borglykke, Anders, et al.
Publicado: (2013)

Genetic Variant SCL2A2 Is Associated with Risk of Cardiovascular Disease – Assessing the Individual and Cumulative Effect of 46 Type 2 Diabetes Related Genetic Variants
por: Borglykke, Anders, et al.
Publicado: (2012)

The PNPLA3 rs738409 G-Allele Associates with Reduced Fasting Serum Triglyceride and Serum Cholesterol in Danes with Impaired Glucose Regulation
por: Krarup, Nikolaj Thure, et al.
Publicado: (2012)

The Birth Weight Lowering C-Allele of rs900400 Near LEKR1 and CCNL1 Associates with Elevated Insulin Release following an Oral Glucose Challenge
por: Andersson, Ehm A., et al.
Publicado: (2011)

Correction: The PNPLA3 rs738409 G-Allele Associates with Reduced Fasting Serum Triglyceride and Serum Cholesterol in Danes with Impaired Glucose Regulation
por: Krarup, Nikolaj Thure, et al.
Publicado: (2012)

Vitamin D Status, Filaggrin Genotype, and Cardiovascular Risk Factors: A Mendelian Randomization Approach
por: Skaaby, Tea, et al.
Publicado: (2013)

The minor C-allele of rs2014355 in ACADS is associated with reduced insulin release following an oral glucose load
por: Hornbak, Malene, et al.
Publicado: (2011)

Determinants of airflow limitation in Danish adults – findings from the Health2006 cohort
por: Baarnes, Camilla Boslev, et al.
Publicado: (2019)

Predictors of accelerated FEV(1) decline in adults with airflow limitation—Findings from the Health2006 cohort
por: Baarnes, Camilla Boslev, et al.
Publicado: (2019)

Grip strength and lower limb extension power in 19–72-year-old Danish men and women: the Health2006 study
por: Aadahl, Mette, et al.
Publicado: (2011)

Genetic Risk Score of 46 Type 2 Diabetes Risk Variants Associates With Changes in Plasma Glucose and Estimates of Pancreatic β-Cell Function Over 5 Years of Follow-Up
por: Andersson, Ehm A., et al.
Publicado: (2013)

Identification of Novel Genetic Determinants of Erythrocyte Membrane Fatty Acid Composition among Greenlanders
por: Andersen, Mette Korre, et al.
Publicado: (2016)

Lifestyle-Related Factors and Atopy in Seven Danish Population-Based Studies from Different Time Periods
por: Skaaby, Tea, et al.
Publicado: (2015)

Trends in treatments of thyroid disease following iodine fortification in Denmark: a nationwide register-based study
por: Møllehave, Line Tang, et al.
Publicado: (2018)

Impact of a vegan diet on the human salivary microbiota
por: Hansen, Tue H., et al.
Publicado: (2018)

Increased frequency of rare missense PPP1R3B variants among Danish patients with type 2 diabetes
por: Niazi, Robina Khan, et al.
Publicado: (2019)

The Type 2 Diabetes Risk Allele of TMEM154-rs6813195 Associates with Decreased Beta Cell Function in a Study of 6,486 Danes
por: Harder, Marie Neergaard, et al.
Publicado: (2015)

Association of Polymorphisms of the CHI3L1 Gene with Asthma and Atopy: A Populations-Based Study of 6514 Danish Adults
por: Rathcke, Camilla Noelle, et al.
Publicado: (2009)

G-allele of Intronic rs10830963 in MTNR1B Confers Increased Risk of Impaired Fasting Glycemia and Type 2 Diabetes Through an Impaired Glucose-Stimulated Insulin Release: Studies Involving 19,605 Europeans
por: Sparsø, Thomas, et al.
Publicado: (2009)

The Association of Alcohol and Alcohol Metabolizing Gene Variants with Diabetes and Coronary Heart Disease Risk Factors in a White Population
por: Husemoen, Lise Lotte N., et al.
Publicado: (2010)

Uncovering the Genetic History of the Present-Day Greenlandic Population
por: Moltke, Ida, et al.
Publicado: (2015)

The effect of drinking water pH on the human gut microbiota and glucose regulation: results of a randomized controlled cross-over intervention
por: Hansen, Tue H., et al.
Publicado: (2018)

Erratum to: ‘Intake of Macro- and Micronutrients in Danish Vegans’
por: Kristensen, Nadja B., et al.
Publicado: (2016)

Intake of macro- and micronutrients in Danish vegans
por: Kristensen, Nadja B., et al.
Publicado: (2015)

Population-based studies of relationships between dietary acidity load, insulin resistance and incident diabetes in Danes
por: Gæde, Joachim, et al.
Publicado: (2018)

Alterations in fecal microbiota composition by probiotic supplementation in healthy adults: a systematic review of randomized controlled trials
por: Kristensen, Nadja B., et al.
Publicado: (2016)

Low birthweight is associated with a higher incidence of type 2 diabetes over two decades independent of adult BMI and genetic predisposition
por: Wibaek, Rasmus, et al.
Publicado: (2023)

Gestational diabetes and the human salivary microbiota: a longitudinal study during pregnancy and postpartum
por: Crusell, Mie K. W., et al.
Publicado: (2020)

Aberrant intestinal microbiota in individuals with prediabetes
por: Allin, Kristine H., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_5vg9b6dhob5qqvhr549o1fftqd