Long-lasting memory deficits in mice withdrawn from cocaine are concomitant with neuroadaptations in hippocampal basal activity, GABAergic interneurons and adult neurogenesis

Cocaine addiction disorder is notably aggravated by concomitant cognitive and emotional pathology that impedes recovery. We studied whether a persistent cognitive/emotional dysregulation in mice withdrawn from cocaine holds a neurobiological correlate within the hippocampus, a limbic region with a k...

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Detalles Bibliográficos
Autores principales: Ladrón de Guevara-Miranda, David, Millón, Carmelo, Rosell-Valle, Cristina, Pérez-Fernández, Mercedes, Missiroli, Michele, Serrano, Antonia, Pavón, Francisco J., Rodríguez de Fonseca, Fernando, Martínez-Losa, Magdalena, Álvarez-Dolado, Manuel, Santín, Luis J., Castilla-Ortega, Estela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374316/
https://www.ncbi.nlm.nih.gov/pubmed/28138095
http://dx.doi.org/10.1242/dmm.026682

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