Systemic autoimmunity induced by the TLR7/8 agonist Resiquimod causes myocarditis and dilated cardiomyopathy in a new mouse model of autoimmune heart disease

Systemic autoimmune diseases such as systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) show significant heart involvement and cardiovascular morbidity, which can be due to systemically increased levels of inflammation or direct autoreactivity targeting cardiac tissue. Despite high cli...

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Detalles Bibliográficos
Autores principales: Hasham, Muneer G., Baxan, Nicoleta, Stuckey, Daniel J., Branca, Jane, Perkins, Bryant, Dent, Oliver, Duffy, Ted, Hameed, Tolani S., Stella, Sarah E., Bellahcene, Mohammed, Schneider, Michael D., Harding, Sian E., Rosenthal, Nadia, Sattler, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374321/
https://www.ncbi.nlm.nih.gov/pubmed/28250051
http://dx.doi.org/10.1242/dmm.027409

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