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Application of Lectin Array Technology for Biobetter Characterization: Its Correlation with FcγRIII Binding and ADCC

Lectin microarray technology was applied to compare the glycosylation pattern of the monoclonal antibody MB311 expressed in SP2.0 cells to an antibody-dependent cellular cytotoxic effector function (ADCC)-optimized variant (MB314). MB314 was generated by a plant expression system that uses genetical...

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Detalles Bibliográficos
Autores principales:	Roucka, Markus, Zimmermann, Klaus, Fido, Markus, Nechansky, Andreas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Technical Note
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374361/ https://www.ncbi.nlm.nih.gov/pubmed/28029136 http://dx.doi.org/10.3390/microarrays6010001

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