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Enhanced store-operated Ca(2+) influx and ORAI1 expression in ventricular fibroblasts from human failing heart
Excessive cardiac fibrosis, characterized by increased collagen-rich extracellular matrix (ECM) deposition, is a major predisposing factor for mechanical and electrical dysfunction in heart failure (HF). The human ventricular fibroblast (hVF) remodeling mechanisms that cause excessive collagen depos...
Autores principales: | Ross, Gracious R., Bajwa, Tanvir, Edwards, Stacie, Emelyanova, Larisa, Rizvi, Farhan, Holmuhamedov, Ekhson L., Werner, Paul, Downey, Francis X., Tajik, A. Jamil, Jahangir, Arshad |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374400/ https://www.ncbi.nlm.nih.gov/pubmed/28126709 http://dx.doi.org/10.1242/bio.022632 |
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