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Aptamers in Bordeaux, 24–25 June 2016

The symposium covered the many different aspects of the selection and the characterization of aptamers as well as their application in analytical, diagnostic and therapeutic areas. Natural and artificial riboswitches were discussed. Recent advances for the design of mutated polymerases and of chemic...

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Detalles Bibliográficos
Autores principales: Toulmé, Jean-Jacques, Giangrande, Paloma H., Mayer, Günter, Suess, Beatrix, Ducongé, Frédéric, Sullenger, Bruce, de Franciscis, Vittorio, Darfeuille, Fabien, Peyrin, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374418/
https://www.ncbi.nlm.nih.gov/pubmed/28117671
http://dx.doi.org/10.3390/ph10010014
Descripción
Sumario:The symposium covered the many different aspects of the selection and the characterization of aptamers as well as their application in analytical, diagnostic and therapeutic areas. Natural and artificial riboswitches were discussed. Recent advances for the design of mutated polymerases and of chemically modified nucleic acid bases that provide aptamers with new properties were presented. The power of aptamer platforms for multiplex analysis of biomarkers of major human diseases was described. The potential of aptamers for the treatment of cancer or cardiovascular diseases was also presented. Brief summaries of the lectures presented during the symposium are given in this report. A second edition of “Aptamers in Bordeaux” will take place on September 2017 (http://www.aptamers-in-bordeaux.com/).