In Search of Small Molecule Inhibitors Targeting the Flexible CK2 Subunit Interface

Protein kinase CK2 is a tetrameric holoenzyme composed of two catalytic (α and/or α’) subunits and two regulatory (β) subunits. Crystallographic data paired with fluorescence imaging techniques have suggested that the formation of the CK2 holoenzyme complex within cells is a dynamic process. Althoug...

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Detalles Bibliográficos
Autores principales: Bestgen, Benoît, Belaid-Choucair, Zakia, Lomberget, Thierry, Le Borgne, Marc, Filhol, Odile, Cochet, Claude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374420/
https://www.ncbi.nlm.nih.gov/pubmed/28165359
http://dx.doi.org/10.3390/ph10010016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374420/
https://www.ncbi.nlm.nih.gov/pubmed/28165359
http://dx.doi.org/10.3390/ph10010016

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