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The Development of CK2 Inhibitors: From Traditional Pharmacology to in Silico Rational Drug Design
Casein kinase II (CK2) is an ubiquitous and pleiotropic serine/threonine protein kinase able to phosphorylate hundreds of substrates. Being implicated in several human diseases, from neurodegeneration to cancer, the biological roles of CK2 have been intensively studied. Upregulation of CK2 has been...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374430/ https://www.ncbi.nlm.nih.gov/pubmed/28230762 http://dx.doi.org/10.3390/ph10010026 |