Structural mechanisms for α-conotoxin activity at the human α3β4 nicotinic acetylcholine receptor

Nicotinic acetylcholine receptors (nAChR) are therapeutic targets for a range of human diseases. α-Conotoxins are naturally occurring peptide antagonists of nAChRs that have been used as pharmacological probes and investigated as drug leads for nAChR related disorders. However, α-conotoxin interacti...

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Detalles Bibliográficos
Autores principales: Abraham, Nikita, Healy, Michael, Ragnarsson, Lotten, Brust, Andreas, Alewood, Paul F., Lewis, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374441/
https://www.ncbi.nlm.nih.gov/pubmed/28361878
http://dx.doi.org/10.1038/srep45466

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374441/
https://www.ncbi.nlm.nih.gov/pubmed/28361878
http://dx.doi.org/10.1038/srep45466

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