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Towards a Humanized Mouse Model of Liver Stage Malaria Using Ectopic Artificial Livers

The malaria liver stage is an attractive target for antimalarial development, and preclinical malaria models are essential for testing such candidates. Given ethical concerns and costs associated with non‐human primate models, humanized mouse models containing chimeric human livers offer a valuable...

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Detalles Bibliográficos
Autores principales: Ng, Shengyong, March, Sandra, Galstian, Ani, Gural, Nil, Stevens, Kelly R., Mota, Maria M., Bhatia, Sangeeta N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374446/
https://www.ncbi.nlm.nih.gov/pubmed/28361899
http://dx.doi.org/10.1038/srep45424