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International incidence and mortality trends of liver cancer: a global profile
We examined the global incidence and mortality rates of liver cancer, and evaluated the association between incidence/mortality and socioeconomic development (Human Development Index [HDI] and Gross Domestic Product [GDP]) using linear regression analysis. The average annual percent change (AAPC) of...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374459/ https://www.ncbi.nlm.nih.gov/pubmed/28361988 http://dx.doi.org/10.1038/srep45846 |
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author | Wong, Martin C. S. Jiang, Johnny Y. Goggins, William B Liang, Miaoyin Fang, Yuan Fung, Franklin D. H. Leung, Colette Wang, Harry H. X. Wong, Grace L. H. Wong, Vincent W.S. Chan, Henry L. Y. |
author_facet | Wong, Martin C. S. Jiang, Johnny Y. Goggins, William B Liang, Miaoyin Fang, Yuan Fung, Franklin D. H. Leung, Colette Wang, Harry H. X. Wong, Grace L. H. Wong, Vincent W.S. Chan, Henry L. Y. |
author_sort | Wong, Martin C. S. |
collection | PubMed |
description | We examined the global incidence and mortality rates of liver cancer, and evaluated the association between incidence/mortality and socioeconomic development (Human Development Index [HDI] and Gross Domestic Product [GDP]) using linear regression analysis. The average annual percent change (AAPC) of the trends was evaluated from join-point regression analysis. The global incidence of liver cancer varied widely by nine-fold, and was negatively correlated with HDI (men: r = −0.232, p = 0.003; women: r = −0.369, p < 0.001) and GDP per capita (men: r = −0.164, p = 0.036; women: r = −0.212, p = 0.007). Its mortality showed a similarly negative correlation with both indices. The greatest incidence rise in men was observed in Poland (AAPC = 17.5, 95% C.I. = 5.6, 30.9) and Brazil (AAPC = 13.2, 95% C.I. = 5.9, 21.0), whereas Germany (AAPC = 6.6, 95% C.I = 2.0, 11.5) and Norway (AAPC = 6.5, 95% C.I. = 3.2, 10.0) had the greatest increase in women. The mortality rates paralleled the incidence rates in most countries. For mortality, Malta (AAPC = 11.5, 95% C.I. = 3.9, 19.8), Australia (AAPC = 6.8, 95% C.I. = 2.2, 11.5) and Norway (APCC = 5.6, 95% C.I. = 2.8, 8.5) reported the biggest increase among men; whilst Australia (AAPC = 13.4, 95% C.I. = 7.8, 19.4) and Singapore (AAPC = 7.7, 95% C.I. = 4.1, 11.5) showed the most prominent rise among women. These epidemiological data identified countries with potentially increasing trends of liver cancer for preventive actions. |
format | Online Article Text |
id | pubmed-5374459 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-53744592017-04-03 International incidence and mortality trends of liver cancer: a global profile Wong, Martin C. S. Jiang, Johnny Y. Goggins, William B Liang, Miaoyin Fang, Yuan Fung, Franklin D. H. Leung, Colette Wang, Harry H. X. Wong, Grace L. H. Wong, Vincent W.S. Chan, Henry L. Y. Sci Rep Article We examined the global incidence and mortality rates of liver cancer, and evaluated the association between incidence/mortality and socioeconomic development (Human Development Index [HDI] and Gross Domestic Product [GDP]) using linear regression analysis. The average annual percent change (AAPC) of the trends was evaluated from join-point regression analysis. The global incidence of liver cancer varied widely by nine-fold, and was negatively correlated with HDI (men: r = −0.232, p = 0.003; women: r = −0.369, p < 0.001) and GDP per capita (men: r = −0.164, p = 0.036; women: r = −0.212, p = 0.007). Its mortality showed a similarly negative correlation with both indices. The greatest incidence rise in men was observed in Poland (AAPC = 17.5, 95% C.I. = 5.6, 30.9) and Brazil (AAPC = 13.2, 95% C.I. = 5.9, 21.0), whereas Germany (AAPC = 6.6, 95% C.I = 2.0, 11.5) and Norway (AAPC = 6.5, 95% C.I. = 3.2, 10.0) had the greatest increase in women. The mortality rates paralleled the incidence rates in most countries. For mortality, Malta (AAPC = 11.5, 95% C.I. = 3.9, 19.8), Australia (AAPC = 6.8, 95% C.I. = 2.2, 11.5) and Norway (APCC = 5.6, 95% C.I. = 2.8, 8.5) reported the biggest increase among men; whilst Australia (AAPC = 13.4, 95% C.I. = 7.8, 19.4) and Singapore (AAPC = 7.7, 95% C.I. = 4.1, 11.5) showed the most prominent rise among women. These epidemiological data identified countries with potentially increasing trends of liver cancer for preventive actions. Nature Publishing Group 2017-03-31 /pmc/articles/PMC5374459/ /pubmed/28361988 http://dx.doi.org/10.1038/srep45846 Text en Copyright © 2017, The Author(s) http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ |
spellingShingle | Article Wong, Martin C. S. Jiang, Johnny Y. Goggins, William B Liang, Miaoyin Fang, Yuan Fung, Franklin D. H. Leung, Colette Wang, Harry H. X. Wong, Grace L. H. Wong, Vincent W.S. Chan, Henry L. Y. International incidence and mortality trends of liver cancer: a global profile |
title | International incidence and mortality trends of liver cancer: a global profile |
title_full | International incidence and mortality trends of liver cancer: a global profile |
title_fullStr | International incidence and mortality trends of liver cancer: a global profile |
title_full_unstemmed | International incidence and mortality trends of liver cancer: a global profile |
title_short | International incidence and mortality trends of liver cancer: a global profile |
title_sort | international incidence and mortality trends of liver cancer: a global profile |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374459/ https://www.ncbi.nlm.nih.gov/pubmed/28361988 http://dx.doi.org/10.1038/srep45846 |
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