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The antimicrobial effects of the alginate oligomer OligoG CF-5/20 are independent of direct bacterial cell membrane disruption

Concerns about acquisition of antibiotic resistance have led to increasing demand for new antimicrobial therapies. OligoG CF-5/20 is an alginate oligosaccharide previously shown to have antimicrobial and antibiotic potentiating activity. We investigated the structural modification of the bacterial c...

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Detalles Bibliográficos
Autores principales: Pritchard, Manon F., Powell, Lydia C., Khan, Saira, Griffiths, Peter C., Mansour, Omar T., Schweins, Ralf, Beck, Konrad, Buurma, Niklaas J., Dempsey, Christopher E., Wright, Chris J., Rye, Philip D., Hill, Katja E., Thomas, David W., Ferguson, Elaine L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374485/
https://www.ncbi.nlm.nih.gov/pubmed/28361894
http://dx.doi.org/10.1038/srep44731