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Tumour blood vessel normalisation by prolyl hydroxylase inhibitor repaired sensitivity to chemotherapy in a tumour mouse model
Blood vessels are important tissue structures that deliver oxygen and nutrition. In tumour tissue, abnormal blood vessels, which are hyperpermeable and immature, are often formed; these tissues also have irregular vascularisation and intravasation. This situation leads to hypoperfusion in tumour tis...
Autores principales: | Koyama, Satoshi, Matsunaga, Shinji, Imanishi, Masaki, Maekawa, Yoichi, Kitano, Hiroya, Takeuchi, Hiromi, Tomita, Shuhei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374523/ https://www.ncbi.nlm.nih.gov/pubmed/28361934 http://dx.doi.org/10.1038/srep45621 |
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