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PCTK3/CDK18 regulates cell migration and adhesion by negatively modulating FAK activity

PCTAIRE kinase 3 (PCTK3) is a member of the cyclin dependent kinase family, but its physiological function remains unknown. We previously reported that PCTK3-knockdown HEK293T cells showed actin accumulation at the leading edge, suggesting that PCTK3 is involved in the regulation of actin reorganiza...

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Detalles Bibliográficos
Autores principales: Matsuda, Shinya, Kawamoto, Kohei, Miyamoto, Kenji, Tsuji, Akihiko, Yuasa, Keizo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374530/
https://www.ncbi.nlm.nih.gov/pubmed/28361970
http://dx.doi.org/10.1038/srep45545

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