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Investigation and identification of protein carbonylation sites based on position-specific amino acid composition and physicochemical features
BACKGROUND: Protein carbonylation, an irreversible and non-enzymatic post-translational modification (PTM), is often used as a marker of oxidative stress. When reactive oxygen species (ROS) oxidized the amino acid side chains, carbonyl (CO) groups are produced especially on Lysine (K), Arginine (R),...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374553/ https://www.ncbi.nlm.nih.gov/pubmed/28361707 http://dx.doi.org/10.1186/s12859-017-1472-8 |