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Comparison of sevoflurane and propofol for laryngeal mask airway insertion and pressor response in patients undergoing gynecological procedures

BACKGROUND AND AIMS: A popular method of providing anesthesia for laryngeal mask airway (LMA) insertion is with the use of propofol. However, bolus propofol has been associated with adverse effects such as hypotension, apnea and pain on injection. Hence, time is needed to search an alternative. We a...

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Autores principales: Chavan, Shirishkumar Gulabrao, Mandhyan, Surita, Gujar, Sandhya Haridas, Shinde, Gourish Prakash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374839/
https://www.ncbi.nlm.nih.gov/pubmed/28413280
http://dx.doi.org/10.4103/joacp.JOACP_313_15
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author Chavan, Shirishkumar Gulabrao
Mandhyan, Surita
Gujar, Sandhya Haridas
Shinde, Gourish Prakash
author_facet Chavan, Shirishkumar Gulabrao
Mandhyan, Surita
Gujar, Sandhya Haridas
Shinde, Gourish Prakash
author_sort Chavan, Shirishkumar Gulabrao
collection PubMed
description BACKGROUND AND AIMS: A popular method of providing anesthesia for laryngeal mask airway (LMA) insertion is with the use of propofol. However, bolus propofol has been associated with adverse effects such as hypotension, apnea and pain on injection. Hence, time is needed to search an alternative. We aimed to compare the induction characteristics, ease of LMA insertion, hemodynamic changes and complications with inhalation of 8% sevoflurane vital capacity breath and propofol. MATERIAL AND METHODS: A prospective randomized study of 60 American Society of Anesthesiologists' Grade I and II patients was conducted and distributed among two groups with 30 each undergoing gynecological procedures under general anesthesia. Group P received the injection propofol and Group S received sevoflurane. At the end point of induction, the LMA insertion was attempted. Scoring systems were used to grade the conditions for insertion of the LMA. Induction, LMA insertion characteristics, hemodynamic changes, complications were assessed. Data were recorded and analyzed. Comparison among the study groups was done with unpaired t-test, Mann–Whitney test and Chi-square test. RESULTS: Sevoflurane took a longer time for induction and for LMA insertion than propofol. There was no statistically significant difference between the two groups, with respect to LMA insertion characteristics, heart rate, mean arterial pressure. It is concluded that sevoflurane is associated with good hemodynamic stability and may prove useful incases where propofol is to be avoided. However, the ease of insertion provided with propofol is better.
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spelling pubmed-53748392017-04-14 Comparison of sevoflurane and propofol for laryngeal mask airway insertion and pressor response in patients undergoing gynecological procedures Chavan, Shirishkumar Gulabrao Mandhyan, Surita Gujar, Sandhya Haridas Shinde, Gourish Prakash J Anaesthesiol Clin Pharmacol Original Article BACKGROUND AND AIMS: A popular method of providing anesthesia for laryngeal mask airway (LMA) insertion is with the use of propofol. However, bolus propofol has been associated with adverse effects such as hypotension, apnea and pain on injection. Hence, time is needed to search an alternative. We aimed to compare the induction characteristics, ease of LMA insertion, hemodynamic changes and complications with inhalation of 8% sevoflurane vital capacity breath and propofol. MATERIAL AND METHODS: A prospective randomized study of 60 American Society of Anesthesiologists' Grade I and II patients was conducted and distributed among two groups with 30 each undergoing gynecological procedures under general anesthesia. Group P received the injection propofol and Group S received sevoflurane. At the end point of induction, the LMA insertion was attempted. Scoring systems were used to grade the conditions for insertion of the LMA. Induction, LMA insertion characteristics, hemodynamic changes, complications were assessed. Data were recorded and analyzed. Comparison among the study groups was done with unpaired t-test, Mann–Whitney test and Chi-square test. RESULTS: Sevoflurane took a longer time for induction and for LMA insertion than propofol. There was no statistically significant difference between the two groups, with respect to LMA insertion characteristics, heart rate, mean arterial pressure. It is concluded that sevoflurane is associated with good hemodynamic stability and may prove useful incases where propofol is to be avoided. However, the ease of insertion provided with propofol is better. Medknow Publications & Media Pvt Ltd 2017 /pmc/articles/PMC5374839/ /pubmed/28413280 http://dx.doi.org/10.4103/joacp.JOACP_313_15 Text en Copyright: © 2017 Journal of Anaesthesiology Clinical Pharmacology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Original Article
Chavan, Shirishkumar Gulabrao
Mandhyan, Surita
Gujar, Sandhya Haridas
Shinde, Gourish Prakash
Comparison of sevoflurane and propofol for laryngeal mask airway insertion and pressor response in patients undergoing gynecological procedures
title Comparison of sevoflurane and propofol for laryngeal mask airway insertion and pressor response in patients undergoing gynecological procedures
title_full Comparison of sevoflurane and propofol for laryngeal mask airway insertion and pressor response in patients undergoing gynecological procedures
title_fullStr Comparison of sevoflurane and propofol for laryngeal mask airway insertion and pressor response in patients undergoing gynecological procedures
title_full_unstemmed Comparison of sevoflurane and propofol for laryngeal mask airway insertion and pressor response in patients undergoing gynecological procedures
title_short Comparison of sevoflurane and propofol for laryngeal mask airway insertion and pressor response in patients undergoing gynecological procedures
title_sort comparison of sevoflurane and propofol for laryngeal mask airway insertion and pressor response in patients undergoing gynecological procedures
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374839/
https://www.ncbi.nlm.nih.gov/pubmed/28413280
http://dx.doi.org/10.4103/joacp.JOACP_313_15
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