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Coccidioidal meningitis complicated by central nervous system vasculitis in a patient with leukemia

Central Nervous System (CNS) vasculitis is the most common life-threatening complication of coccidioidal meningitis. It is manifested by cerebral ischemia, hemorrhage, and infarction. We report a case of CNS vasculitis in a patient receiving chemotherapy and review of the literature on coccidioidal...

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Detalles Bibliográficos
Autores principales: Tager, Dany, Hatch, Anne, Segar, Jennifer, Roller, Brentin, Al Mohajer, Mayar, Zangeneh, Tirdad T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374848/
https://www.ncbi.nlm.nih.gov/pubmed/28386527
http://dx.doi.org/10.1016/j.mmcr.2017.03.003
Descripción
Sumario:Central Nervous System (CNS) vasculitis is the most common life-threatening complication of coccidioidal meningitis. It is manifested by cerebral ischemia, hemorrhage, and infarction. We report a case of CNS vasculitis in a patient receiving chemotherapy and review of the literature on coccidioidal meningitis. The patient was treated with combination antifungal therapy and a short course of high dose corticosteroids with a modest improvement in her neurological examination after initiation of steroids.