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Crosstalk Between Transforming Growth Factor Beta-2 and Toll-Like Receptor 4 in the Trabecular Meshwork

PURPOSE: The trabecular meshwork (TM) is involved in the outflow of aqueous humor and intraocular pressure (IOP) regulation. Regulation of the extracellular matrix (ECM) by TGFβ2 signaling pathways in the TM has been extensively studied. Recent evidence has implicated toll-like receptor 4 (TLR4) in...

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Detalles Bibliográficos
Autores principales: Hernandez, Humberto, Medina-Ortiz, Wanda E., Luan, Tomi, Clark, Abbot F., McDowell, Colleen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374883/
https://www.ncbi.nlm.nih.gov/pubmed/28346614
http://dx.doi.org/10.1167/iovs.16-21331