The recent advances of phenotypes in acute exacerbations of COPD

Exacerbations of COPD are clinically relevant events with therapeutic and prognostic implications. Yet, significant heterogeneity of clinical presentation and disease progression exists within acute exacerbations of COPD (AECOPD). Currently, different phenotypes have been widely used to describe the...

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Autores principales: Zhou, Aiyuan, Zhou, Zijing, Zhao, Yiyang, Chen, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5375638/
https://www.ncbi.nlm.nih.gov/pubmed/28392685
http://dx.doi.org/10.2147/COPD.S128604
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author Zhou, Aiyuan
Zhou, Zijing
Zhao, Yiyang
Chen, Ping
author_facet Zhou, Aiyuan
Zhou, Zijing
Zhao, Yiyang
Chen, Ping
author_sort Zhou, Aiyuan
collection PubMed
description Exacerbations of COPD are clinically relevant events with therapeutic and prognostic implications. Yet, significant heterogeneity of clinical presentation and disease progression exists within acute exacerbations of COPD (AECOPD). Currently, different phenotypes have been widely used to describe the characteristics among patients with AECOPD. This has proved to be significant in the treatment and prediction of the outcomes of the disease. In this review of published literature, the phenotypes of AECOPD were classified according to etiology, inflammatory biomarkers, clinical manifestation, comorbidity, the frequency of exacerbations, and so on. This review concentrates on advancements in the use of phenotypes of AECOPD.
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spelling pubmed-53756382017-04-07 The recent advances of phenotypes in acute exacerbations of COPD Zhou, Aiyuan Zhou, Zijing Zhao, Yiyang Chen, Ping Int J Chron Obstruct Pulmon Dis Review Exacerbations of COPD are clinically relevant events with therapeutic and prognostic implications. Yet, significant heterogeneity of clinical presentation and disease progression exists within acute exacerbations of COPD (AECOPD). Currently, different phenotypes have been widely used to describe the characteristics among patients with AECOPD. This has proved to be significant in the treatment and prediction of the outcomes of the disease. In this review of published literature, the phenotypes of AECOPD were classified according to etiology, inflammatory biomarkers, clinical manifestation, comorbidity, the frequency of exacerbations, and so on. This review concentrates on advancements in the use of phenotypes of AECOPD. Dove Medical Press 2017-03-27 /pmc/articles/PMC5375638/ /pubmed/28392685 http://dx.doi.org/10.2147/COPD.S128604 Text en © 2017 Zhou et al. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Review
Zhou, Aiyuan
Zhou, Zijing
Zhao, Yiyang
Chen, Ping
The recent advances of phenotypes in acute exacerbations of COPD
title The recent advances of phenotypes in acute exacerbations of COPD
title_full The recent advances of phenotypes in acute exacerbations of COPD
title_fullStr The recent advances of phenotypes in acute exacerbations of COPD
title_full_unstemmed The recent advances of phenotypes in acute exacerbations of COPD
title_short The recent advances of phenotypes in acute exacerbations of COPD
title_sort recent advances of phenotypes in acute exacerbations of copd
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5375638/
https://www.ncbi.nlm.nih.gov/pubmed/28392685
http://dx.doi.org/10.2147/COPD.S128604
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