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Supportive Noninvasive Tool for the Diagnosis of Breast Cancer Using a Thermographic Camera as Sensor

Breast cancer is the leading disease in incidence and mortality among women in developing countries. The opportune diagnosis of this disease strengthens the survival index. Mammography application is limited by age and periodicity. Temperature is a physical magnitude that can be measured by using mu...

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Autores principales: Garduño-Ramón, Marco Antonio, Vega-Mancilla, Sofia Giovanna, Morales-Henández, Luis Alberto, Osornio-Rios, Roque Alfredo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5375783/
https://www.ncbi.nlm.nih.gov/pubmed/28273793
http://dx.doi.org/10.3390/s17030497
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author Garduño-Ramón, Marco Antonio
Vega-Mancilla, Sofia Giovanna
Morales-Henández, Luis Alberto
Osornio-Rios, Roque Alfredo
author_facet Garduño-Ramón, Marco Antonio
Vega-Mancilla, Sofia Giovanna
Morales-Henández, Luis Alberto
Osornio-Rios, Roque Alfredo
author_sort Garduño-Ramón, Marco Antonio
collection PubMed
description Breast cancer is the leading disease in incidence and mortality among women in developing countries. The opportune diagnosis of this disease strengthens the survival index. Mammography application is limited by age and periodicity. Temperature is a physical magnitude that can be measured by using multiple sensing techniques. IR (infrared) thermography using commercial cameras is gaining relevance in industrial and medical applications because it is a non-invasive and non-intrusive technology. Asymmetrical temperature in certain human body zones is associated with cancer. In this paper, an IR thermographic sensor is applied for breast cancer detection. This work includes an automatic breast segmentation methodology, to spot the hottest regions in thermograms using the morphological watershed operator to help the experts locate the tumor. A protocol for thermogram acquisition considering the required time to achieve a thermal stabilization is also proposed. Breast thermograms are evaluated as thermal matrices, instead of gray scale or false color images, increasing the certainty of the provided diagnosis. The proposed tool was validated using the Database for Mastology Research and tested in a voluntary group of 454 women of different ages and cancer stages with good results, leading to the possibility of being used as a supportive tool to detect breast cancer and angiogenesis cases.
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spelling pubmed-53757832017-04-10 Supportive Noninvasive Tool for the Diagnosis of Breast Cancer Using a Thermographic Camera as Sensor Garduño-Ramón, Marco Antonio Vega-Mancilla, Sofia Giovanna Morales-Henández, Luis Alberto Osornio-Rios, Roque Alfredo Sensors (Basel) Article Breast cancer is the leading disease in incidence and mortality among women in developing countries. The opportune diagnosis of this disease strengthens the survival index. Mammography application is limited by age and periodicity. Temperature is a physical magnitude that can be measured by using multiple sensing techniques. IR (infrared) thermography using commercial cameras is gaining relevance in industrial and medical applications because it is a non-invasive and non-intrusive technology. Asymmetrical temperature in certain human body zones is associated with cancer. In this paper, an IR thermographic sensor is applied for breast cancer detection. This work includes an automatic breast segmentation methodology, to spot the hottest regions in thermograms using the morphological watershed operator to help the experts locate the tumor. A protocol for thermogram acquisition considering the required time to achieve a thermal stabilization is also proposed. Breast thermograms are evaluated as thermal matrices, instead of gray scale or false color images, increasing the certainty of the provided diagnosis. The proposed tool was validated using the Database for Mastology Research and tested in a voluntary group of 454 women of different ages and cancer stages with good results, leading to the possibility of being used as a supportive tool to detect breast cancer and angiogenesis cases. MDPI 2017-03-03 /pmc/articles/PMC5375783/ /pubmed/28273793 http://dx.doi.org/10.3390/s17030497 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Garduño-Ramón, Marco Antonio
Vega-Mancilla, Sofia Giovanna
Morales-Henández, Luis Alberto
Osornio-Rios, Roque Alfredo
Supportive Noninvasive Tool for the Diagnosis of Breast Cancer Using a Thermographic Camera as Sensor
title Supportive Noninvasive Tool for the Diagnosis of Breast Cancer Using a Thermographic Camera as Sensor
title_full Supportive Noninvasive Tool for the Diagnosis of Breast Cancer Using a Thermographic Camera as Sensor
title_fullStr Supportive Noninvasive Tool for the Diagnosis of Breast Cancer Using a Thermographic Camera as Sensor
title_full_unstemmed Supportive Noninvasive Tool for the Diagnosis of Breast Cancer Using a Thermographic Camera as Sensor
title_short Supportive Noninvasive Tool for the Diagnosis of Breast Cancer Using a Thermographic Camera as Sensor
title_sort supportive noninvasive tool for the diagnosis of breast cancer using a thermographic camera as sensor
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5375783/
https://www.ncbi.nlm.nih.gov/pubmed/28273793
http://dx.doi.org/10.3390/s17030497
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