Organic cation transporter 1 (OCT1) is involved in pentamidine transport at the human and mouse blood-brain barrier (BBB)

Pentamidine is an effective trypanocidal drug used against stage 1 Human African Trypanosomiasis (HAT). At the blood-brain barrier (BBB), it accumulates inside the endothelial cells but has limited entry into the brain. This study examined transporters involved in pentamidine transport at the human...

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Detalles Bibliográficos
Autores principales: Sekhar, Gayathri N., Georgian, Ana R., Sanderson, Lisa, Vizcay-Barrena, Gema, Brown, Rachel C., Muresan, Paula, Fleck, Roland A., Thomas, Sarah A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376088/
https://www.ncbi.nlm.nih.gov/pubmed/28362799
http://dx.doi.org/10.1371/journal.pone.0173474

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