Novel Multiarm Polyethylene glycol-Dihydroartemisinin Conjugates Enhancing Therapeutic Efficacy in Non-Small-Cell Lung Cancer

The clinical application of dihydroartemisinin (DHA) has been hampered due to its poor water-solubility. To overcome this hurdle, we devised a novel polymer-drug conjugate, multiarm polyethylene glycol-dihydroartemisinin (PEG-DHA), made by linking DHA with multiarm polyethylene glycol. Herein, we in...

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Detalles Bibliográficos
Autores principales: Dai, Lin, Wang, Luying, Deng, Lihong, Liu, Jing, Lei, Jiandu, Li, Dan, He, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376196/
https://www.ncbi.nlm.nih.gov/pubmed/25070490
http://dx.doi.org/10.1038/srep05871

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376196/
https://www.ncbi.nlm.nih.gov/pubmed/25070490
http://dx.doi.org/10.1038/srep05871

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